Real-World Adherence Patterns to Antidepressants

Keyloun KR, et al. (2017) — Adherence and Persistence Across Antidepressant Therapeutic Classes in MDD Using a large US insurance claims dataset, this study found that adherence to initial antidepressant medication drops sharply over time (e.g., ~41 % at 3 months to ~21 % at 12 months).

The study highlights the challenge of maintaining continuous oral antidepressant use in everyday clinical practice, reinforcing the case for alternative delivery systems.

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