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Introducing 428Pharma.

The Right Medication to the Right Patient

Our Story

A team of former senior directors from big pharma with combined 60+ years and more than 60 projects in diagnostics and 505(b)(2) drug development have secured exclusive worldwide rights to two high value assets, made available by a recent well-publicized R&D restructuring and divestment.

Our Portfolio

Escitalopram LAI (Long Acting Injectable)

An early stage asset at formulation stage.  With the discovery and patenting of a novel salt to Escitalopram we can bring the first SSRI depot to the market.

 

  • First depot injection for SSRI for a vast depression market estimated at $15.8Bn in 2025

  • 505(b)(2) truncated development with LOE Q4 2038.  Opportunity to out-license end of phase I

  • Estimated potential peak sales of over $1.5Bn (US and EU big 5)

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CGRP mAb Diagnostic

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Teva, in conjunction with Professor Rami Burstein from Harvard, discovered and patented a novel method of identifying the 50% of migraine patients who will respond to the CGRP class of drugs.  This late stage asset can be brought to the market with a single clinical trial and generate a royalty stream to fund additional projects.

  • Diagnostic will offer best in class differentiation in a market expected to be worth $7Bn in 2025

  • Increased market share in a highly competitive market (Amgen/Novartis, Lilly, Lundbeck & Teva)

  • LOE patent extension of up to seven years on multibillion-dollar sales

We are in diligence on two additional projects that are complementary to our portfolio.

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Why 428 Pharma?

Experienced pharma team with over 60 projects between the team in the area of diagnostics and 505(b)(2) drug development

Two projects gives a diverse and de-risked pipeline. Rapid time to market and revenue stream to fund additional projects

Get in Touch

+972 (0) 54 888 5275

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